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ACROBiosystems FITC-Labeled Human CD8 alpha&beta (CD8A&CD8B) Heterodimer Protein, His Tag&Tag Free

Marca:  ACROBiosystems CDA-HF2W4-200ug

Dettagli aggiuntivi : Peso : 0.00010kg

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Codice prodotto. 17116191

  • dietro preventivo / 200µg

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Descrizione

Descrizione

Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. CD8A forms disulfide-linked heterodimers with CD8B at the cell surface. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells. Additionally, CD8B plays a critical role in thymic selection of CD8+ T-cells. A palmitoylation site in the cytoplasmic tail of CD8B chain contributes to partitioning of CD8 into the plasma membrane lipid rafts where signaling proteins are enriched.

FITC-Labeled Human CD8A&CD8B Heterodimer Protein, His Tag&Tag Free, produced by co-expression of CD8 alpha and CD8 beta, has a calculated MW of 19.5 kDa (CD8 alpha) and 22.1 kDa (CD8 beta). Subunit CD8 alpha is fused with a polyhistidine tag at the C-term
Specifica

Specifica

NP_001759.3 (CD8A)/NP_004922.1 (CD8B)
19.5 kDa (CD8A) and 22.1 kDa (CD8B)
200 µg
Ser 22 - Asp 182 (CD8A) and Leu 22 - Pro 170 (CD8B)
CD8 alpha and beta,CD8A and CD8B
FITC Labeled Protein
PBS, pH7.4
HEK293
Human
Powder
>90% as determined by SDS-PAGE
FITC-Labeled Human CD8A&CD8B; Heterodimer Protein, His Tag&Tag; Free (CDA-HF2W4) is expressed from human 293 cells (HEK293). It contains AA Ser 22 - Asp 182 (CD8A) and Leu 22 - Pro 170 (CD8B) (Accession # P01732-1 (CD8A) and P10966-1 (CD8B)). It is the FITC labeled form of Human CD8A&CD8B; Heterodimer Protein, His Tag&Tag; Free (CDA-H52W5).
-20°C, avoid light
CD8 alpha and beta
His Tag
Less than 1.0 EU / µg by the LAL method.
Fluorescent labeled protein
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