missing translation for 'onlineSavingsMsg'
Learn More

HDAC4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 17449-1-AP-20UL

Dettagli aggiuntivi : Peso : 0.00010kg

 vedi altre versioni di questo prodotto

Codice prodotto. 16897334

  • 121.38€ / 20µL

Spedizione stimata: 28-09-2022
per visualizzare lo stock disponibile
Aggiungi al carrello

Descrizione

Descrizione

This antibody is a rabbit polyclonal antibody raised against an internal region of human HDAC4. The calculated molecular weight of HDAC4 is 106 kDa, but modified HDAC4 is about 140 kDa.

Histone deacetylase 4 (HDAC4) is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3, and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. HDAC4 is also involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. It is also involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. Mutations to the HDAC4 gene have been found in Brachydactyly-mental retardation syndrome (BDMR).
Specifica

Specifica

HDAC4
Polyclonal
Unconjugated
HDAC4
HA6116, HD4, HDAC A, HDAC4, HDACA, histone deacetylase 4, KIAA0288
Rabbit
Antigen Affinity Chromatography
RUO
208727, 363287, 9759
-20°C
Liquid
Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin)
0.21 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P56524, Q6NZM9, Q99P99
Hdac4
HDAC4 Fusion Protein Ag11572
20 μL
Primary
Rat, Mouse, Human
Antibody
IgG
Videos
SDS
Documenti
Certificati
Offerte speciali

Offerte speciali