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ACROBiosystems Human CD133 Full Length Protein, His Tag (Nanodisc)
Marca: ACROBiosystems CD3-H52H1-500ug
Dettagli aggiuntivi : Peso : 0.00010kg
Descrizione
Prominin-1 is also known as CD133, Antigen AC133, PROM1, PROML1 and MSTP061. Is used as marker for hematopoietic stem and progenitor cells (HSPC) for somatic stem cell isolation. May play a role in cell differentiation, proliferation and apoptosis . Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.
Nanodiscs are a new class of model membranes that are being used to solubilize and study a range of integral membrane proteins (mp, full length CD133) and membrane-associated proteins. The Nanodisc bilayer is bounded by a membrane scaffold protein (MSP1D1Specifica
| NP_006008.1 | |
| 500 μg | |
| Gly 20 - His 865 | |
| CD133,PROM1,PROML1,Prominin-1,AC133 | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >90% as determined by SDS-PAGE. |
| 97.2 kDa | |
| Human CD133 Full Length, His Tag (Nanodisc) (CD3-H52H1) is expressed from human 293 cells (HEK293). It contains AA Gly 20 - His 865 (Accession # O43490-1). | |
| -20°C | |
| CD133 | |
| Human | |
| 20 mM HEPES, 150 mM NaCl, pH7.5 | |
| HEK293 | |
| Bio-Markers & CD Antigens |