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ACROBiosystems Human CD3 epsilon Protein, Mouse IgG2a Fc Tag
Marca: ACROBiosystems CDN-H5253-100ug
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Descrizione
CD3e molecule, epsilon is also known as CD3E, is a T-cell surface single-pass type I membrane glycoprotein. CD3E contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. CD3E plays an essential role in T-cell development, and defects in CD3E gene cause severe immunodeficiency. CD3E gene has also been linked to a susceptibility to type I diabetes in women. CD3E has been shown to interact with TOP2B, CD3EAP and NCK2.
This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 38.6 kDa.Specifica
| NP_000724.1 | |
| 100 μg | |
| Asp 23 - Asp 126 | |
| FLJ18683,T3E,TCRE,CD3E,CD3-epsilon | |
| Unconjugated | |
| Mouse IgG Fc Tag | |
| Powder |
| 38.6 kDa | |
| Human CD3 epsilon, Mouse IgG2a Fc Tag (CDN-H5253) is expressed from human 293 cells (HEK293). It contains AA Asp 23 - Asp 126 (Accession # NP_000724.1). | |
| -20°C | |
| CD3 epsilon | |
| Human | |
| HEK293 | |
| Bio-Markers & CD Antigens |