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ACROBiosystems Human GCGR / Glucagon receptor Protein, His Tag (MALS verified)

Marca:  ACROBiosystems GCR-H52H3-50ug

Dettagli aggiuntivi : Peso : 0.00010kg

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Codice prodotto. 17296210

  • 396.58€ / 50µg

Spedizione stimata: 15-02-2023
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Descrizione

Descrizione

G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 14.9 kDa. The protein migrates as 28-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Specifica

Specifica

NP_000151.1
>90% as determined by SDS-PAGE.
Human GCGR, His Tag (GCR-H52H3) is expressed from human 293 cells (HEK293). It contains AA Ala 26 - Lys 136 (Accession # P47871-1).
-20°C
GCGR
His Tag
Less than 0.1 EU / µg by the LAL method.
Powder
Human
14.9 kDa
50 µg
Ala 26 - Lys 136
Glucagon R, GCGR,Glucagon receptor
Unconjugated
PBS, pH7.4
HEK293
Bio-Markers & CD Antigens
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SDS
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