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ACROBiosystems Human IL-31 RA Protein, His Tag (MALS verified)
Marca: ACROBiosystems ILA-H52H7-1mg
Dettagli aggiuntivi : Peso : 0.00010kg
Descrizione
Interleukin-31 receptor subunit alpha is a protein that in humans is encoded by the IL31RA gene, also known as IL-31 receptor subunit alpha, IL-31RA, GLM-R, Gp130-like receptor, CRL3, GPL. Oncostatin M receptor (OSMR) and IL31RA form the heterodimeric receptor through which IL31 signals. IL31RA is a strong activator of STAT3 and STAT5, whereas STAT1 is only marginally tyrosine-phosphorylated. dditionally, demonstrate Jak1 binding to GPL and its activation in heteromeric complexes with the OSMRbeta but also in a homomeric receptor complex.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 59.0 kDa. The protein migrates as 90-115 KDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Specifica
| 59.0 kDa | |
| Human IL-31 RA, His Tag (ILA-H52H7) is expressed from human 293 cells (HEK293). It contains AA Ala 20 - Glu 519 (Accession # Q8NI17-1). | |
| -20°C | |
| IL-31 RA | |
| Human | |
| PBS, pH7.4 | |
| HEK293 | |
| Bio-Markers & CD Antigens |
| 1 mg | |
| Ala 20 - Glu 519 | |
| IL-31 RA,IL-31 RA,hGLM-R,CRL3,GPL,ZcytoR17,GLM-R,IL-31 R-alpha,Gp130-like receptor | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE. |