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ACROBiosystems Human IL-31 RA Protein, His Tag (MALS verified)

Marca:  ACROBiosystems ILA-H52H7-1mg

Dettagli aggiuntivi : Peso : 0.00010kg

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Codice prodotto. 17226270

  • dietro preventivo / 1mg

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Descrizione

Descrizione

Interleukin-31 receptor subunit alpha is a protein that in humans is encoded by the IL31RA gene, also known as IL-31 receptor subunit alpha, IL-31RA, GLM-R, Gp130-like receptor, CRL3, GPL. Oncostatin M receptor (OSMR) and IL31RA form the heterodimeric receptor through which IL31 signals. IL31RA is a strong activator of STAT3 and STAT5, whereas STAT1 is only marginally tyrosine-phosphorylated. dditionally, demonstrate Jak1 binding to GPL and its activation in heteromeric complexes with the OSMRbeta but also in a homomeric receptor complex.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 59.0 kDa. The protein migrates as 90-115 KDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Specifica

Specifica

59.0 kDa
1 mg
Ala 20 - Glu 519
IL-31 RA,IL-31 RA,hGLM-R,CRL3,GPL,ZcytoR17,GLM-R,IL-31 R-alpha,Gp130-like receptor
Unconjugated
PBS, pH7.4
HEK293
Bio-Markers & CD Antigens
>95% as determined by SDS-PAGE.
Human IL-31 RA, His Tag (ILA-H52H7) is expressed from human 293 cells (HEK293). It contains AA Ala 20 - Glu 519 (Accession # Q8NI17-1).
-20°C
IL-31 RA
His Tag
Less than 1.0 EU / µg by the LAL method.
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