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ACROBiosystems Human LGR5 / GPR49 protein, His Tag
Marca: ACROBiosystems LG5-H52H3-100ug
Dettagli aggiuntivi : Peso : 0.00010kg
Descrizione
LGR5 (also known as GPR49) is a seven-transmembrane protein of the class A Rhodopsin-like family of GPCRs. LGR5 and LGR4 bind the R-spondins with high affinity and mediate the potentiation of Wnt/β-catenin signaling by enhancing Wnt-induced LRP6 phosphorylation. The LGR5/RSPO complex could promote Wnt signalling via the neutralization of two transmembrane E3 ligases, RNF43 and ZNRF3.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 62.0 kDa. The protein migrates as 66-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Specifica
| NP_003658.1 | |
| 100 μg | |
| Gly 22 - Arg 561 | |
| LGR5, GPR49, GPR67, G-protein coupled receptor 49, G-protein coupled receptor 67, G-protein coupled receptor HG38, Leucine-rich repeat-containing G-protein coupled receptor 5 | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >90% as determined by SDS-PAGE. |
| 62.0 kDa | |
| Human LGR5, His Tag (LG5-H52H3) is expressed from human 293 cells (HEK293). It contains AA Gly 22 - Arg 561 (Accession # O75473-1). | |
| -20°C | |
| LGR5 | |
| Human | |
| PBS, pH7.4 | |
| HEK293 | |
| Other Recombinant Proteins |