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Epredia™ Lab Vision™ XPF Ab-1 Mouse Monoclonal Antibody, 200μg/mL, BSA and azide
Provide accurate, reproducible results with the Epredia™ XPF Ab-1, Mouse Monoclonal Antibody.
Marca: Epredia™ MS-1381-P1ABX
Dettagli aggiuntivi : Peso : 1.00000kg
Descrizione
The structure-specific ERCC1/XPF endonuclease complex is implicated in the repair of two distinct types of lesions in DNA: NER for UV-induced lesions and bulky chemical adducts; and recombination repair of the very genotoxic interstrand cross-links. NER mechanism involves dual incisions on both sides of the damage catalyzed by two nucleases. In mammalian cells XPG cleaves 3' of the DNA lesion while the ERCC1-XPF complex makes the 5' incision.Host Species: Mouse
Clone: 219
Isotype: IgG2/κ
Species Reactivity: Human. Others not known.
Epitope: Not determined
Immunogen: Recombinant human XPF protein
Molecular Weight: ∽110kDa
Positive Control: MCF-7 cells or human tonsil
Cellular Localization: Nuclear
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
Note:
USA: RUO; Int'l: RUO
Specifica
| XPF Ab-1 | |
| Monoclonal | |
| 1mg/mL | |
| Mouse | |
| 100 μL | |
| DNA Repair | |
| Human | |
| IgG2 |
| Immunohistochemistry (Paraffin), Western Blot | |
| 219 | |
| Unconjugated | |
| Recombinant human XPF protein | |
| RUO | |
| Primary | |
| Concentrated |