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LRRC15 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marca: Thermo Scientific PA557298
Dettagli aggiuntivi : Peso : 0.02000kg
Descrizione
Immunogen sequence: NWLLLNQPRL GTDTVPVCFS PANVRGQSLI IINVNVAVPS VHVPEVPSYP ETPWYPDTPS YPDTTSVSST TELTSPVEDY TDLTTIQVTD DRSVW Highest antigen sequence identity to the following orthologs: Mouse - 65%, Rat - 73%.
Leucine-rich repeats (LRRs) are 20-29 amino acid motifs that mediate protein-protein interactions. The primary function of these motifs is to provide a versatile structural framework for the formation of these protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutations in genes encoding LRR-containing proteins. The leucine-rich repeat-containing protein 15 (LRRC15, also designated LIB) is a 581 amino acid protein that contains 15 LRR repeats and is involved in cell-cell and/or -extracellular matrix interactions. LRRC15 is frequently overexpressed in multiple tumor types, most notably breast carcinoma. It is also associated with the pathogenesis of Alzheimer's disease.Specifica
LRRC15 | |
Polyclonal | |
Unconjugated | |
LRRC15 | |
5430427N11Rik; hLib; leucine rich repeat containing 15; Leucine-rich repeat protein induced by amyloid-beta; leucine-rich repeat protein induced by beta amyloid; leucine-rich repeat protein induced by beta-amyloid; leucine-rich repeat protein induced by beta-amyloid homolog; Leucine-rich repeat-containing protein 15; LIB; Lrrc15; rLib | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
131578 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry | |
0.15 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
Q8TF66 | |
LRRC15 | |
Recombinant protein corresponding to Human LRRC15 | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Research Use Only