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LY96/MD2 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 11784-1-AP-20UL

Dettagli aggiuntivi : Peso : 0.00010kg

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Codice prodotto. 16899083

  • 121.38€ / 20µL

Spedizione stimata: 10-10-2022
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Descrizione

Descrizione

MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS. The specificity of this response is determined by the species of MD-2; e. g., human MD-2 transfected into mouse cells can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4.
Specifica

Specifica

LY96/MD2
Polyclonal
Unconjugated
LY96
ESOP 1, ESOP1, Ly 96, LY96, lymphocyte antigen 96, MD 2, MD2, Protein MD 2
Rabbit
Antigen Affinity Chromatography
RUO
23643
-20°C
Liquid
Western Blot, Immunohistochemistry (Paraffin)
0.13 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q9Y6Y9
LY96
LY96/MD2 Fusion Protein Ag2447
20 μL
Primary
Human
Antibody
IgG
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