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MEK2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 11049-1-AP-150UL

Dettagli aggiuntivi : Peso : 0.00010kg

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Codice prodotto. 16897853

  • 325.38€ / 150µL

Spedizione stimata: 28-09-2022
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Descrizione

Descrizione

11049-1-AP can recognize both MEK2 and MEK1.

MEK1 (Mitogen activated protein kinase kinase 1) catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. MEK1 activates ERK1 and ERK2 MAP kinases. Mitogen activated protein kinase kinase 2 (MEK2 or MAPKK2) is a member of a family of tyrosine/threonine protein kinases that activate the ERK1 and 2 and MAPK enzymes by phosphorylating both residues within the threonine/glutamate/tyrosine (TEY) motif in the activation loop. MEK1 and 2 are also activated by dual phosphorylation, which occurs on serine 218 and 222, in the activation loop of the MEK. Threonine 292 of MEK1 is phosphorylated by ERK 2, which serves as a negative feedback loop by suppressing activation of MEK1.
Specifica

Specifica

MEK2
Polyclonal
Unconjugated
MAP2K2
ERK activator kinase 2, MAP kinase kinase 2, MAP2K2, MAPK/ERK kinase 2, MAPKK 2, MAPKK2, MEK 2, MEK2, MKK2, PRKMK2
Rabbit
Antigen Affinity Chromatography
RUO
26396, 5605, 58960
-20°C
Liquid
Western Blot, Immunoprecipitation, Immunofluorescence, Immunocytochemistry
0.27 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P36506, P36507, Q63932
Map2k2
MEK2 Fusion Protein Ag1481
150 μL
Primary
Rat, Mouse, Human
Antibody
IgG
Videos
SDS
Documenti
Certificati
Offerte speciali

Offerte speciali