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MT-ND3 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA550711
Additional Details : Peso : 0.01000kg
Description
The antibody detects endogenous levels of total MT-ND3 protein.
NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by trans-location of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits. A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 3 (ND3) localizes to the hydrophobic protein fragment of complex I. Mutations in the gene encodiing for ND3 may be associated with Parkinson disease.Specifications
| MT-ND3 | |
| Polyclonal | |
| Unconjugated | |
| MT-ND3 | |
| 1.6.5.3; mitochondrially encoded NADH dehydrogenase 3; Mtnd3; mt-Nd3; NADH dehydrogenase subunit 3; NADH3; NADH-ubiquinone oxidoreductase chain 3; ND3 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 4537 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin) | |
| 1.5 mg/mL | |
| PBS with 40% glycerol and 0.05% sodium azide; pH 7.4 | |
| P03897 | |
| MT-ND3 | |
| Synthetic peptide corresponding to a region derived from internal residues of human mitochondrially encoded NADH dehydrogenase 3 | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |