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OCT4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 11263-1-AP-150UL

Dettagli aggiuntivi : Peso : 0.00010kg

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Codice prodotto. 16898213

  • 349.00€ / 150µL

Spedizione stimata: 19-12-2022
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Descrizione

Descrizione

Oct4 is a maternally expressed octamer-binding protein that was the first transcription factor described for the early stages of development. Oct4 is one of the four Yamaka factors, necessary for embryonic stem cell pluripotency. Pluripotent stem (iPS) cells, can be created by expressing Oct4 and the transcription factors Sox2, Klf4 and Lin28 along with c-Myc in mouse fibroblasts. More recently, experiments have demonstrated that iPS cells could be generated using expression plasmids expressing Oct4, Sox2, KlfF4 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine. A translocation of this gene with the Ewing′s sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation.
Specifica

Specifica

OCT4
Polyclonal
Unconjugated
POU5F1
Oct 3, Oct 4, OCT3, OCT3/4, OCT4, Octamer binding protein 3, Octamer binding protein 4, OTF 3, OTF3, OTF4, POU class 5 homeobox 1, POU5F1
Rabbit
Antigen Affinity Chromatography
RUO
18999, 294562, 5460
-20°C
Liquid
Western Blot
0.36 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P20263, Q01860
Pou5f1
OCT4 Fusion Protein Ag1794
150 μL
Primary
Rat, Mouse, Human
Antibody
IgG
Videos
SDS
Documenti
Certificati
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Offerte speciali