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OXCT1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 12175-1-AP-20UL

Dettagli aggiuntivi : Peso : 0.00010kg

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Codice prodotto. 16899723

  • 121.38€ / 20µL

Spedizione stimata: 10-10-2022
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Descrizione

Descrizione

This antibody specifically recognizes endogenous OXCT1.

The maf oncogene was identified by structural analysis of the AS42 avian transforming retrovirus genome. The Maf family is divided into two subclasses, large Mafs (vMaf, cMaf, MafB and Nrl) and small Mafs (MafF, MafK, and MafG). Both subclasses contain leucinezipper motifs, which allow homodimerization as well as heterodimerization with a variety of other bZip transcription factors. Large Mafs also contain an acidic transactivation domain absent in the small Maf proteins. Although they do not possess inherent transactivation activity, small Maf proteins can act as positive regulators of transcription by targeting transcriptionally active dimerization partners to specific DNA regulatory elements. Conversely, small Mafs can act also as negative regulators of transcription by recruiting transcriptional repressors or by forming homodimers that can replace active dimers. Human MafF was isolated in a yeast one-hybrid system from a human myometrium cDNA library. Human MAFF encodes a 164 amino acids proten. Like other small MAFF proteins, it contains an extended leucine zipper structure and lacks an N-terminal transactivating domain. The three small Maf proteins have been implicated in a number of physiological processes, including development, differentiation, haematopoiesis and stress response. Interestingly, these three proteins regulate the stress response via different mechanisms.
Specifica

Specifica

OXCT1
Polyclonal
Unconjugated
OXCT1
3 oxoacid CoA transferase 1, OXCT, OXCT1, SCOT, SCOT s
Rabbit
Antigen Affinity Chromatography
RUO
5019, 67041, 690163
-20°C
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunofluorescence, Immunocytochemistry, Immunoprecipitation
0.25 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P55809, Q9D0K2
OXCT1
OXCT1 Fusion Protein Ag2818
20 μL
Primary
Mouse, Rat, Human
Antibody
IgG
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