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PKC iota Mouse anti-Human, Mouse, Rat, Clone: 3A1B6, Proteintech

Mouse Monoclonal Antibody

Marca:  Proteintech 66493-1-IG-150UL

Dettagli aggiuntivi : Peso : 0.00010kg

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Codice prodotto. 16898415

  • 349.00€ / 150µL

Spedizione stimata: 16-12-2022
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Descrizione

Descrizione

This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefore protects leukemia cells against drug-induced apoptosis. There is a single exon pseudogene mapped on chromosome X.
Specifica

Specifica

PKC iota
Monoclonal
1 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
F1M7Y5, P41743, Q62074
Prkci
PKC iota Fusion Protein Ag4990
150 μL
Primary
Rat, Mouse, Human
Antibody
IgG2a
Western Blot, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry
3A1B6
Unconjugated
PRKCI
aPKC lambda/iota, DXS1179E, PKCI, PRKC lambda/iota, PRKCI, Protein kinase C iota type, protein kinase C, iota
Mouse
Protein A
RUO
18759, 5584, 84006
-20°C
Liquid
Videos
SDS
Documenti
Certificati
Offerte speciali

Offerte speciali