missing translation for 'onlineSavingsMsg'
Learn More

PRKAR1A Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 20358-1-AP-20UL

Dettagli aggiuntivi : Peso : 0.00010kg

 vedi altre versioni di questo prodotto

Codice prodotto. 16899884

  • 121.38€ / 20µL

Spedizione stimata: 05-10-2022
per visualizzare lo stock disponibile
Aggiungi al carrello

Descrizione

Descrizione

The second messenger cyclic AMP (cAMP) mediates diverse cellular responses to external signals such as proliferation, ion transport, regulation of metabolism and gene transcription by activation of the cAMP-dependent protein kinase (cAPK or PKA). Activation of PKA occurs when cAMP binds to the two regulatory subunits of the tetrameric PKA holoenzyme, resulting in release of active catalytic subunits. Four different PKA regulatory subunits have been identified, designated Ia, Ib, IIa and IIb. The PKA Ia reg protein is a tissue-specific extinguisher that downregulates the expression of seven liver genes in hepatoma x fibroblast hybrids. Functional null mutations in the gene that codes for PKA Ia reg cause Carney complex (CNC). CNC is an autosomal domit multiple neoplasia syndrome. CNC is associated with a variety of characterized symptoms such as cardiac and other myxomas, spotty skin pigmentation, endocrine tumors and psammomatous melanotic schwannomas.
Specifica

Specifica

PRKAR1A
Polyclonal
Unconjugated
PRKAR1A
CAR, CNC, CNC1, PKR1, PPNAD1, PRKAR1, PRKAR1A, Tissue specific extinguisher 1, TSE1
Rabbit
Antigen Affinity Chromatography
RUO
19084, 25725, 5573
-20°C
Liquid
Immunofluorescence, Western Blot, Immunohistochemistry (Paraffin), Immunocytochemistry
0.62 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P09456, P10644, Q9DBC7
Prkar1a
PRKAR1A Fusion Protein Ag14216
20 μL
Primary
Human, Rat, Mouse
Antibody
IgG
Videos
SDS
Documenti
Certificati
Offerte speciali

Offerte speciali