missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Pyruvate Carboxylase Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marca: Invitrogen PA550101
Dettagli aggiuntivi : Peso : 0.01000kg
Description
The antibody detects endogenous levels of total Pyruvate Carboxylase protein.
Pyruvate Carboxylase requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency.Specifications
| Pyruvate Carboxylase | |
| Polyclonal | |
| Unconjugated | |
| PC | |
| EC 6.4.1.1; Pc; Pcb; Pcx; PYC; pyruvate carboxylase; pyruvate carboxylase, mitochondrial; pyruvate decarboxylase; pyruvic carboxylase | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 18517, 18563, 5091 | |
| -20°C | |
| Liquid |
| Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| P11498, Q05920 | |
| PC, Pcx | |
| Synthesized peptide derived from internal of human PC. | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |