ACROBiosystems Rat CD22 Protein, His Tag
Marca: ACROBiosystems CD2-R52H3-100ug
Dettagli aggiuntivi : Peso : 0.00010kg
The Cd22 gene is conserved in human, chimpanzee, dog, cow, mouse, and frog. 170 organisms, including rat, have orthologs with human gene Cd22. B-cell receptor CD22 is also known as Sialic acid-binding Ig-like lectin 2 (Siglec-2), B-lymphocyte cell adhesion molecule (BL-CAM), T-cell surface antigen Leu-14, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. CD22 mediates B-cell B-cell interactions, and may be involved in the localization of B-cells in lymphoid tissues. Siglec-2 / CD22 binds sialylated glycoproteins, one of which is CD45. Siglec2 / CD22 plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 77.1 kDa.
|Trp 24 - Arg 692|
|CD22, CD22 antigen (Predicted), CD22 molecule|
|Rat CD22, His Tag (CD2-R52H3) is expressed from human 293 cells (HEK293). It contains AA Trp 24 - Arg 692 (Accession # D3ZD88-1).|
|Bio-Markers & CD Antigens|