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ACROBiosystems SARS-CoV-2 S protein (F817P, A892P, A899P, A942P, K986P, V987P), His Tag (MALS verified)

Marca:  ACROBiosystems SPN-C52Hd-500ug

Dettagli aggiuntivi : Peso : 0.00010kg

 vedi altre versioni di questo prodotto

Codice prodotto. 17286550

  • 4029.41€ / 500µg
Spedizione stimata: 07-03-2024
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Descrizione

Descrizione

It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 138.2 kDa. The protein migrates as 75-85 kDa, 90-100 kDa and 150-160 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Specifica

Specifica

QHD43416.1
500 µg
Val 16 - Pro 1213
Spike,S protein,Spike glycoprotein,S glycoprotein,COVID-19
Unconjugated
His Tag
Less than 1.0 EU / µg by the LAL method.
Powder
>95% as determined by SDS-PAGE.
138.2 kDa
SARS-CoV-2 S protein, His Tag (SPN-C52Hd) is expressed from human 293 cells (HEK293). It contains AA Val 16 - Pro 1213 (Accession # QHD43416.1). Proline substitutions (F817P, A892P, A899P, A942P, K986P, V987P) are introduced to stabilize the trimeric prefusion state of SARS-CoV-2 S protein.
-20°C
S protein
SARS-CoV-2
PBS
HEK293
Viral Proteins
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