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SPDEF Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 11467-1-AP-20UL

Dettagli aggiuntivi : Peso : 0.00010kg

 vedi altre versioni di questo prodotto

Codice prodotto. 16898563

  • 121.38€ / 20µL

Spedizione stimata: 11-10-2022
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Descrizione

Descrizione

PDEF (prostate-derived Ets factor) is a 37.5- kDa protein that acts as an androgen-independent transcriptional activator for the PSA (prostate specific antigen) promoter. It also interacts directly with the DNA binding domain of androgen receptor and enhances androgen-mediated activation of the PSA promoter. PDEF was shown to have transcript levels 192-fold higher in the peripheral blood of some breast cancer patients in comparison with normal individuals. PDEF mRNA is also frequently over-expressed in human breast tumors as well as in human ovarian tumors. In ovarian tumors, PDEF expression seems to down-modulate maligt potential, and thus provides a rationale to screen for drugs that induce PDEF expression in epithelial ovarian tumors.
Specifica

Specifica

SPDEF
Polyclonal
Unconjugated
SPDEF
PDEF, Prostate derived Ets factor, Prostate specific Ets, PSE, RP11 375E1__A.3, SPDEF
Rabbit
Antigen Affinity Chromatography
RUO
25803, 30051, 689210
-20°C
Liquid
Western Blot
0.31 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
O95238, Q9WTP3
SPDEF
SPDEF Fusion Protein Ag2020
20 μL
Primary
Human, Rat, Mouse
Antibody
IgG
Videos
SDS
Documenti
Certificati
Offerte speciali

Offerte speciali