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UBE2C Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 12134-2-AP-20UL

Dettagli aggiuntivi : Peso : 0.00010kg

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Codice prodotto. 16899663

  • 121.38€ / 20µL

Spedizione stimata: 11-10-2022
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Descrizione

Descrizione

This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is required for the destruction of mitotic cyclins and for cell cycle progression, and may be involved in cancer progression. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes ′Lys-11′- and ′Lys-48′-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating ′Lys-11′-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit.
Specifica

Specifica

UBE2C
Polyclonal
Unconjugated
UBE2C
UBCH10, UBE2C, Ubiquitin carrier protein C, Ubiquitin protein ligase C
Rabbit
Antigen Affinity Chromatography
RUO
11065, 296368, 68612
-20°C
Liquid
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
0.33 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
O00762, Q9D1C1
Ube2c
UBE2C Fusion Protein Ag2780
20 μL
Primary
Human, Mouse, Rat
Antibody
IgG
Videos
SDS
Documenti
Certificati
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