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H3CCH3OOH3CNHOHNOH3CCH3NHOHNONO

CAS RN 868540-17-4

IUPAC Nome: 4-methyl-N-(1-{[4-methyl-1-(2-methyloxiran-2-yl)-1-oxopentan-2-yl]carbamoyl}-2-phenylethyl)-2-{2-[2-(morpholin-4-yl)acetamido]-4-phenylbutanamido}pentanamide
Sinonimi: carfilzomib
Peso molecolare (g/mol): 719.92
Formula molecolare: C40H57N5O7
InChi Key: BLMPQMFVWMYDKT-UHFFFAOYNA-N
SMILES: CC(C)CC(NC(=O)C(CCC1=CC=CC=C1)NC(=O)CN1CCOCC1)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CC(C)C)C(=O)C1(C)CO1
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  • (1)
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2

Carfilzomib, TRC

CAS: 868540-17-4 Sinonimo: L-Phenylalaninamide, (αS)-α-[[2-(4-morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyl-2-oxiranyl]carbonyl]butyl]-∣L-Phenylalaninamide, (αS)-α-[(4-morpholinylacetyl)amino]benzenebutanoyl-L-leucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyloxiranyl]carbonyl]butyl]- (9CI)∣(αS)-α-[[2-(4-Morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyl-2-oxiranyl]carbonyl]butyl]-L-phenylalaninamide∣Carfilzomib∣Kyprolis∣PR 171

Sinonimo L-Phenylalaninamide, (αS)-α-[[2-(4-morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyl-2-oxiranyl]carbonyl]butyl]-∣L-Phenylalaninamide, (αS)-α-[(4-morpholinylacetyl)amino]benzenebutanoyl-L-leucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyloxiranyl]carbonyl]butyl]- (9CI)∣(αS)-α-[[2-(4-Morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyl-2-oxiranyl]carbonyl]butyl]-L-phenylalaninamide∣Carfilzomib∣Kyprolis∣PR 171
CAS 868540-17-4
3

Carfilzomib, Mikromol™

Discover Mikromol - your trusted source for high-quality pharmaceutical reference standards. Supporting accurate, compliant analysis with ISO 17034-accredited materials designed for confidence in every result.

4

R&D Systems™ Carfilzomib

A Tocris product, part of R&D Systems. Potent irreversible proteasome inhibitor; active in vivo

Formula molecolare C40H57N5O7
CAS 868540-17-4
Purezza 0.98
Conservazione consigliata Store at -20°C
Materiale o nome chimico (αS)-α-[[2-(4-Morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-N-[(1 S)-3-methyl-1-[[(2 R)-2-methyl-2-oxiranyl]carbonyl]butyl]-L-phenylalaninamide
Bersaglio Proteasome Inhibitors
5

Carfilzomib, MedChemExpress

MedChemExpress Carfilzomib (PR-171) is an irreversible proteasome inhibitor with an IC50 of 5 nM in ANBL-6 and RPMI 8226 cells.

ENCOMPASS_PREFERRED
Peso formulazione 719.91
Sinonimo PR-171
Note sul grado di purezza Research
Colore White
Forma fisica Powder
Molecular Weight (g/mol) 719.91
Conservazione consigliata Powder -20°C 3 years, 4°C 2 years∣The compound is unstable in solutions, freshly prepared is recommended.
SMILES C[C@@]1(C([C@H](CC(C)C)NC([C@@H](NC([C@H](CC(C)C)NC([C@@H](NC(CN2CCOCC2)=O)CCC3=CC=CC=C3)=O)=O)CC4=CC=CC=C4)=O)=O)OC1
Durata utile Powder -20°C 3 years, 4°C 2 years∣The compound is unstable in solutions, freshly prepared is recommended.
Formula molecolare C40H57N5O7
Percent Purity 97.0%
Informazioni di solubilità DMF : ≥ 100 mg/mL (138.91 mM) ∣DMSO : 50 mg/mL (69.45 mM; Need ultrasonic)
CAS 868540-17-4
Da utilizzare con (applicazione) Cancer-Kinase/protease
Materiale o nome chimico Carfilzomib
Grado Research