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AMPD1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 19780-1-AP-20UL

Dettagli aggiuntivi : Peso : 0.00010kg

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Codice prodotto. 16899254

  • 121.38€ / 20µL

Spedizione stimata: 04-10-2022
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Descrizione

Descrizione

The antibody is specific to AMPD1.

AMP deaminase (AMPD) is an allosteric enzyme involved in the regulation of adenosine metabolism. It catalyzes a central reaction in purine nucleotide biosynthesis where AMP is deaminated to IMP, liberating ammonia. There are three functional isoforms of AMPD. AMPD1 (E.C. No 3.5.4.6. ) is the skeletal muscle-specific isoform M located in type II muscle fibers, neuromuscular junctions and in capillaries. This protein is the predomit member of AMPD multi-gene family and is considered as the sensor of the cell′s changing energy requirements. AMPD1 deficiency causes irregular muscle metabolism due to lower rate of ATP degradation, phosphocreatine hydrolysis and accumulation of lactic acid. Mutated AMPD1 expression has been detected in neuromuscular disorders, exercise-induced skeletal muscle myopathies and congestive heart failures due to coronary artery diseases.
Specifica

Specifica

AMPD1
Polyclonal
Unconjugated
AMPD1
AMP deaminase 1, AMP deaminase isoform M, AMPD1, MAD, MADA, Myoadenylate deaminase
Rabbit
Antigen Affinity Chromatography
RUO
229665, 25028, 270
-20°C
Liquid
Western Blot
0.13 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P10759, P23109, Q3V1D3
Ampd1
Peptide
20 μL
Primary
Human, Mouse, Rat
Antibody
IgG
Videos
SDS
Documenti
Certificati
Offerte speciali

Offerte speciali