missing translation for 'onlineSavingsMsg'
Learn More

ACROBiosystems Biotinylated Human Syndecan-1 Protein, Fc, Avitag™

Biotinylated Protein

Marca:  ACROBiosystems SY1-H82F3-25ug

Dettagli aggiuntivi : Peso : 0.00010kg

 vedi altre versioni di questo prodotto

Codice prodotto. 17116791

  • dietro preventivo / 25µg

Questo articolo richiede un aggiornamento del prezzo prima di essere ordinato.

Richiedi qui il prezzo per questo articolo.


Descrizione

Descrizione

Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca2+ release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs (Soluble NSF Attachment Protein REceptors) at presynaptic plasma membrane in conjunction with cysteine string protein-alpha/DNAJC5. This chaperone activity is important to sustain normal SNARE-complex assembly during aging. Plays also a role in the regulation of the dopamine neurotransmission by associating with the dopamine transporter (DAT1) and thereby modulating its activity.

This protein carries a human IgG1 Fc tag at the C-terminus, followed by a Avi tag (Avitag™). The protein has a calculated MW of 52.0 kDa. The protein migrates as 60-66 kDa under reducing (R) condition (SDS-PAGE) due to Glycosylation.
Specifica

Specifica

Powder
>90% as determined by SDS-PAGE
Biotinylated Human Syndecan-1, Fc,Avitag (SY1-H82F3) is expressed from human 293 cells (HEK293). It contains AA Gln 23 - Gly 254 (Accession # P18827-1).
-20°C
Syndecan-1
Fc Tag and Avi Tag
Less than 1.0 EU / µg by the LAL method.
MABSol™ Biotin Labeled Proteins
52.0 kDa
25 µg
Gln 23 - Gly 254
SDC1,Syndecan-1,CD138,SYND1,SDC
Precision Avi
PBS, pH7.4
HEK293
Human
Videos
SDS
Documenti

Documenti

Certificati
Offerte speciali

Offerte speciali