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CD41/Integrin alpha 2b Mouse anti-Human, Clone: 6D7C5, Proteintech
Mouse Monoclonal Antibody
Marca: Proteintech 60350-1-IG-150UL
Dettagli aggiuntivi : Peso : 0.00010kg
Descrizione
CD41 (platelet glycoprotein IIb, ITGA2B) is composed of two subunits -120 kDa a, alpha and 23 kDa b, beta- that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. CD41 is also involved in blood coagulation by mediating platelet aggregation. Upon blood vessel damage, CD41 binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during the early stages of hematopoietic differentiation. Diseases associated with CD41 dysfunction include Glansmann Thrombasthenia, and Platelet type-16 bleeding disorder.Specifica
CD41/Integrin alpha 2b | |
Monoclonal | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
P08514 | |
ITGA2B | |
Peptide | |
150 μL | |
Primary | |
Human | |
Antibody | |
IgG1 |
Western Blot | |
6D7C5 | |
Unconjugated | |
ITGA2B | |
CD41, CD41/Integrin alpha 2b, CD41B, GP2B, GPalpha IIb, GPIIb, GTA, HPA3, Integrin alpha IIb, ITGA2B, ITGAB | |
Mouse | |
Protein G | |
RUO | |
3674 | |
-20°C | |
Liquid |