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CDK2 Mouse anti-Human, Clone: 4E2E10, Proteintech
Mouse Monoclonal Antibody
Marca: Proteintech 60312-1-IG-150UL
Dettagli aggiuntivi : Peso : 0.00010kg
Descrizione
p33cdk2 associates with cyclin A in human cells. Kinase activity associated with cyclin A-cdc2 is found only in G2-phase. Cdk2 also complexes with cyclins E, D1, and D3. Cyclin E-cdk2 kinase is active in the G1- and S-phases of the cell cycle and is important (as does cyclin A-cdk2) for the progression from G1-to S-phase. The levels of cyclin A-cdk2 is maximal at the G1/S transition and both cdk2 and cyclin A are found associated with DNA in the initiation complex during replication. Rb protein acts as substrate for cdk2-cyclin E and/or cdk2-cyclin A in vivo. Cdk2 is activated and specifically localized to the nucleus during late G1-, S-, and G2-phase.Specifica
CDK2 | |
Monoclonal | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
P24941 | |
CDK2 | |
CDK2 Fusion Protein Ag21310 | |
150 μL | |
Primary | |
Human | |
Antibody | |
IgM |
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot | |
4E2E10 | |
Unconjugated | |
CDK2 | |
CDK2, Cell division protein kinase 2, cyclin dependent kinase 2, p33 protein kinase, p33(CDK2) | |
Mouse | |
Caprylic Acid Precipitation | |
RUO | |
1017 | |
-20°C | |
Liquid |