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CDK2 Mouse anti-Human, Clone: 4E2E10, Proteintech

Mouse Monoclonal Antibody

Marca:  Proteintech 60312-1-IG-150UL

Dettagli aggiuntivi : Peso : 0.00010kg

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Codice prodotto. 16897395

  • 399.00€ / 150µL
Spedizione stimata: 08-05-2024
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Descrizione

Descrizione

p33cdk2 associates with cyclin A in human cells. Kinase activity associated with cyclin A-cdc2 is found only in G2-phase. Cdk2 also complexes with cyclins E, D1, and D3. Cyclin E-cdk2 kinase is active in the G1- and S-phases of the cell cycle and is important (as does cyclin A-cdk2) for the progression from G1-to S-phase. The levels of cyclin A-cdk2 is maximal at the G1/S transition and both cdk2 and cyclin A are found associated with DNA in the initiation complex during replication. Rb protein acts as substrate for cdk2-cyclin E and/or cdk2-cyclin A in vivo. Cdk2 is activated and specifically localized to the nucleus during late G1-, S-, and G2-phase.
Specifica

Specifica

CDK2
Monoclonal
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P24941
CDK2
CDK2 Fusion Protein Ag21310
150 μL
Primary
Human
Antibody
IgM
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
4E2E10
Unconjugated
CDK2
CDK2, Cell division protein kinase 2, cyclin dependent kinase 2, p33 protein kinase, p33(CDK2)
Mouse
Caprylic Acid Precipitation
RUO
1017
-20°C
Liquid
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