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Dystroglycan Mouse anti-Human, Mouse, Porcine, Rat, Clone: 2B1G12, Proteintech

Mouse Monoclonal Antibody

Marca:  Proteintech 66735-1-IG-150UL

Dettagli aggiuntivi : Peso : 0.00010kg

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Codice prodotto. 16898885

  • 325.38€ / 150µL

Spedizione stimata: 11-10-2022
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Descrizione

Descrizione

Dystroglycan is a laminin binding component of the dystrophin-glycoprotein complex which provides a linkage between the subsarcolemmal cytoskeleton and the extracellular matrix. Dystroglycan 1 is a candidate gene for the site of the mutation in autosomal recessive muscular dystrophies. The dramatic reduction of dystroglycan 1 in Duchenne muscular dystrophy leads to a loss of linkage between the sarcolemma and extracellular matrix, rendering muscle fibers more susceptible to necrosis. Dystroglycan also functions as dual receptor for agrin and laminin-2 in the Schwann cell membrane. The muscle and nonmuscle isoforms of dystroglycan differ by carbohydrate moieties but not protein sequence. Alternative splicing results in multiple transcript variants all encoding the same protein.
Specifica

Specifica

Dystroglycan
Monoclonal
1 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q14118, Q29243, Q62165
Dag1
Dystroglycan Fusion Protein Ag27222
150 μL
Primary
Rat, Porcine, Mouse, Human
Antibody
IgG1
Western Blot, Immunohistochemistry (Paraffin)
2B1G12
Unconjugated
DAG1
156DAG, A3a, AGRNR, Alpha DG Beta dystroglycan, Beta DG, DAG, DAG1, Dystroglycan
Mouse
Protein G
RUO
100620392, 114489, 13138, 1605
-20°C
Liquid
Videos
SDS
Documenti
Certificati
Offerte speciali

Offerte speciali