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ACROBiosystems FITC-Labeled Human CLEC12A / MICL / CLL-1 Protein, His Tag

Marca:  ACROBiosystems CLA-HF247-200ug

Dettagli aggiuntivi : Peso : 0.00010kg

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Codice prodotto. 17106261

  • dietro preventivo / 200µg

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Descrizione

Descrizione

CLEC12A (C-type lectin domain family 12 member A) is also known as CLL1, DCAL2, MICL. Clec12a is an inhibitory receptor for uric acid crystals that regulates inflammation in response to cell death. Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. Evidence of distinct disease propagating stem cells in myelodysplastic syndrome (MDS) has emerged in recent years. The role of CLEC12A in MDS, however, remains to be elucidated. Furthermore, CLEC12A has been proposed as a promising marker of leukaemic stem cells in AML.

This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 25.6 kDa. The protein migrates as 35-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Specifica

Specifica

NP_612210.4
25.6 kDa
200 µg
His 65 - Ala 265
CLEC12A,MICL,CLL-1,CLL1,DCAL2,DCAL-2,CD371
FITC Labeled Protein
PBS, pH7.4
HEK293
Human
Powder
>90% as determined by SDS-PAGE
FITC-Labeled Human CLEC12A, His Tag (CLA-HF247) is expressed from human 293 cells (HEK293). It contains AA His 65 - Ala 265 (Accession # Q5QGZ9-2). It is the FITC labeled form of Human CLEC12A, His Tag (CLA-H5245).
-20°C, avoid light
CLEC12A
His Tag
Less than 1.0 EU / µg by the LAL method.
Fluorescent labeled protein
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