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IGF1R beta chain Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 20254-1-AP-20UL

Dettagli aggiuntivi : Peso : 0.00010kg

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Codice prodotto. 16899774

  • 121.38€ / 20µL

Spedizione stimata: 10-10-2022
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Descrizione

Descrizione

This antibody raised against a synthesized polypeptide (CGVLVLRASFDERQPYAH) corresponding to 1332-1348aa of human IGF1R protein recognizes beta subunit of IGF1R.

IGF1R (Insulin-like Growth Factor1 Receptor) is a receptor tyrosine kinase that mediates actions of insulin-like growth factor 1 (IFG1). It binds IGF1 with high affinity and IGF2/insulin with lower affinity. Activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survial of maligt cells. Ligand binding activates the receptor kinase and leads to receptor autophosphorylation and tyrosines phosphorylation of multiple substrates that function as signaling adapter proteins.
Specifica

Specifica

IGF1R beta chain
Polyclonal
Unconjugated
IGF1R
CD221, IGF I receptor, IGF1R, IGFIR, IGFR, JTK13
Rabbit
Antigen Affinity Chromatography
RUO
16001, 25718, 3480
-20°C
Liquid
Western Blot, Immunohistochemistry (Paraffin), Immunoprecipitation
0.22 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P08069, P24062, Q60751
IGF1R
Peptide
20 μL
Primary
Rat, Human, Mouse
Antibody
IgG
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