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KCNQ2 Mouse anti-Human, Mouse, Porcine, Rat, Clone: 1D4A1, Proteintech
Mouse Monoclonal Antibody
Marca: Proteintech 66774-1-IG-150UL
Dettagli aggiuntivi : Peso : 0.00010kg
Descrizione
KCNQs are members of the voltage-dependent non-inactivating potassium channel family. Currently there are five known KNCQs (KCNQ1-5) found in the central nervous system and KNCQ2 and 3 have demonstrated their importance in M-current activation. Studies have shown that KCNQ2 and KCNQ3 form heteromultimers that, when formed, substantially increase the M-current. Inhibition of M-current controls neuron excitability throughout the nervous system as well as the responsiveness to synaptic inputs. Genetic mutations in these proteins have been linked to disorders such as benign familial neonatal convulsions (BFNC), deafness, neuropathic pain and epilepsy.Specifica
KCNQ2 | |
Monoclonal | |
1 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
O43526, O88943, Q9Z351 | |
Kcnq2 | |
KCNQ2 Fusion Protein Ag25781 | |
150 μL | |
Primary | |
Human, Mouse, Porcine, Rat | |
Antibody | |
IgG1 |
Western Blot | |
1D4A1 | |
Unconjugated | |
KCNQ2 | |
BFNC, EBN, EBN1, ENB1, HNSPC, KCNA11, KCNQ2, KQT like 2, KV7.2, KVEBN1 | |
Mouse | |
Protein G | |
RUO | |
110257402, 16536, 170848, 3785 | |
-20°C | |
Liquid |