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KIFAP3 Mouse anti-Human, Mouse, Rat, Clone: 7C9F2, Proteintech
Mouse Monoclonal Antibody
Marca: Proteintech 60266-1-IG-150UL
Dettagli aggiuntivi : Peso : 0.00010kg
Descrizione
The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras; one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 ′Armadillo′ repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein. Several transcript variants encoding different isoforms have been found for this gene.Specifica
KIFAP3 | |
Monoclonal | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
P70188, Q92845 | |
Kifap3 | |
KIFAP3 Fusion Protein Ag20809 | |
150 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG2a |
Immunohistochemistry (Paraffin), Western Blot | |
7C9F2 | |
Unconjugated | |
KIFAP3 | |
KAP 3, KAP3, KIF3AP, KIFAP3, kinesin associated protein 3, SMAP, Smg GDS, Smg GDS associated protein | |
Mouse | |
Protein A | |
RUO | |
16579, 22920, 289168 | |
-20°C | |
Liquid |