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Epredia™ Lab Vision™ Cytokeratin 17 Ab-1, Mouse Monoclonal Antibody
Obtain accurate, reproducible results in immunohistochemistry and immunofluorescence experiments with Epredia™ Cytokeratin 17 Ab-1, Mouse Monoclonal Antibody.
Brand: Epredia™ MS-489-S
Additional Details : Peso : 0.00250kg
Description
The type I keratin 17 (K17) shows a peculiar localization in human epithelial appendages including hair follicles, which undergo a growth cycle throughout adult life. Additionally K17 is induced, along with K6 and K16, early after acute injury to human skin. Predominant expression of K17 and the frequent expression of K8 and K19, with little K6/K16 and K1/K10 expression are the characteristic features of basal cell carcinomas (BCC), suggesting that BCC is differentiated towards undifferentiated follicular epithelia, most probably hair bulge cells.Host Species: Mouse
Clone: E3
Isotype: IgG2b/κ
Species Reactivity: Human and Rat. Others not known.
Epitope: Not determined
Immunogen: Cytokeratin preparation from rat enterocytes
Molecular Weight: 46 kDa
Positive Control: Squamous cell CA, Skin
Cellular Localization: Cytoplasmic
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Immunofluorescence
Specifications
| Cytokeratin 17 Ab-1 | |
| Monoclonal | |
| Unconjugated | |
| Keratin preparation from rat enterocytes | |
| 1 mL | |
| Cytoskeletal Protein | |
| Human, Rat | |
| IgG2b κ |
| Immunofluorescence, Immunohistochemistry (Paraffin) | |
| E3 | |
| Mouse | |
| Squamous cell CA, skin | |
| IVD | |
| Primary | |
| Concentrated |