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MGMT Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 17195-1-AP-150UL

Dettagli aggiuntivi : Peso : 0.00010kg

 vedi altre versioni di questo prodotto

Codice prodotto. 16897044

  • 325.38€ / 150µL

Spedizione stimata: 29-09-2022
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Descrizione

Descrizione

O6-Methylguanine-DNA Methyltransferase (MGMT) is an important DNA repair protein involved in tumor cell resistance to the cytostatic activity of chemotherapeutic alkylating agents. This protein is also effective in protecting normal cells against the genotoxic and carcinogenic effects of DNA alkylation. The alkylating drug resistance is caused by MGMT′s ability to remove DNA alkyl groups introduced in the O6 position of guanine. MGMT is expressed in highly variable amounts, depending upon the cell and tissue type, species, and cellular growth characteristics. In addition, MGMT activity varies among groups of tumors and within a particular type of tumor.
Specifica

Specifica

MGMT
Polyclonal
Unconjugated
MGMT
MGMT
Rabbit
Antigen Affinity Chromatography
RUO
4255
-20°C
Liquid
Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin)
0.34 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P16455
MGMT
MGMT Fusion Protein Ag9996
150 μL
Primary
Human
Antibody
IgG
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