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MIB1 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marca: Proteintech 11893-1-AP-150UL
Dettagli aggiuntivi : Peso : 0.00010kg
Descrizione
MIB is an E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. This protein positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. MIB probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis.Specifica
| MIB1 | |
| Polyclonal | |
| Unconjugated | |
| MIB1 | |
| DAPK interacting protein 1, DIP 1, DIP1, KIAA1323, MIB, MIB1, Mind bomb homolog 1, ZZANK2, ZZZ6 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 57534 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| 0.23 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| Q86YT6 | |
| MIB1 | |
| MIB1 Fusion Protein Ag2507 | |
| 150 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |