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MIB1 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marca: Proteintech 11893-1-AP-150UL
Dettagli aggiuntivi : Peso : 0.00010kg
Descrizione
MIB is an E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. This protein positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. MIB probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis.Specifica
MIB1 | |
Polyclonal | |
Unconjugated | |
MIB1 | |
DAPK interacting protein 1, DIP 1, DIP1, KIAA1323, MIB, MIB1, Mind bomb homolog 1, ZZANK2, ZZZ6 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
57534 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
0.23 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
Q86YT6 | |
MIB1 | |
MIB1 Fusion Protein Ag2507 | |
150 μL | |
Primary | |
Human | |
Antibody | |
IgG |