Learn More
ACROBiosystems Mouse LY75 / CD205 Protein, His Tag
Marca: ACROBiosystems LY5-M52H5-100ug
Dettagli aggiuntivi : Peso : 0.00010kg
Descrizione
lymphocyte antigen 75 (Ly 75, also known as CD205, CLEC13B, GP200-MR6 and DEC-205, is a type I transmembrane protein that is primarily expressed on dendritic cells and thymic epithelial cells. LY75 functions as an endocytic receptor for antigens. MEN1309/OBT076, the first antibody drug targeting CD205, has shown strong preclinical anti-tumor activity in lymphoma. After being verified as a single drug in vivo, the antibody-drug conjugate has a synergistic effect with the BCL2 inhibitor Venetoclax and the anti-cd20 monoclonal antibody rituximab.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 190.0 kDa.Specifica
190.0 kDa | |
Mouse LY75, His Tag (LY5-M52H5) is expressed from human 293 cells (HEK293). It contains AA Ser 28 - Asp 1667 (Accession # Q60767-1). | |
-20°C | |
LY75 | |
Mouse | |
HEK293 | |
Bio-Markers & CD Antigens |
100 μg | |
Ser 28 - Asp 1667 | |
LY75,CD205,DEC-205,CLEC13B,Lymphocyte antigen 75,gp200-MR6 | |
Unconjugated | |
His Tag | |
Powder |