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ACROBiosystems Mouse LY75 / CD205 Protein, His Tag

Marca:  ACROBiosystems LY5-M52H5-100ug

Dettagli aggiuntivi : Peso : 0.00010kg

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Codice prodotto. 17256310

  • dietro preventivo / 100µg

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Descrizione

Descrizione

lymphocyte antigen 75 (Ly 75, also known as CD205, CLEC13B, GP200-MR6 and DEC-205, is a type I transmembrane protein that is primarily expressed on dendritic cells and thymic epithelial cells. LY75 functions as an endocytic receptor for antigens. MEN1309/OBT076, the first antibody drug targeting CD205, has shown strong preclinical anti-tumor activity in lymphoma. After being verified as a single drug in vivo, the antibody-drug conjugate has a synergistic effect with the BCL2 inhibitor Venetoclax and the anti-cd20 monoclonal antibody rituximab.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 190.0 kDa.
Specifica

Specifica

Powder
100 μg
Ser 28 - Asp 1667
LY75,CD205,DEC-205,CLEC13B,Lymphocyte antigen 75,gp200-MR6
Unconjugated
HEK293
Mouse
190.0 kDa
Mouse LY75, His Tag (LY5-M52H5) is expressed from human 293 cells (HEK293). It contains AA Ser 28 - Asp 1667 (Accession # Q60767-1).
-20°C
LY75
His Tag
Bio-Markers & CD Antigens
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