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ACROBiosystems Mouse Nectin-4 Protein, Fc Tag (MALS verified)

Marca:  ACROBiosystems NE4-M5257-100ug

Dettagli aggiuntivi : Peso : 0.00010kg

 vedi altre versioni di questo prodotto

Codice prodotto. 17226340

  • dietro preventivo / 100µg

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Descrizione

Descrizione

Nectin-4 (gene name PVRL4, poliovirus receptor-like 4) is a 66 kDa type I transmembrane glycoprotein belonging to the Nectin family of Ig superfamily proteins. Nectins are cell adhesion molecules that play a key role in various biological processes such as polarity, proliferation, differentiation and migration, for epithelial, endothelial, immune and neuronal cells, during development and adult life. Nectin-4 is a tumor-associated antigen in 50%, 49% and 86%o of breast, ovarian and lung carcinomas, respectively, mostly on tumors of bad prognosis. Its expression is not detected in the corresponding normal tissues.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 60.8 kDa. The protein migrates as 65-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Specifica

Specifica

NP_082169.2
>95% as determined by SDS-PAGE.
Mouse Nectin-4, Fc Tag (NE4-M5257) is expressed from human 293 cells (HEK293). It contains AA Gly 31 - Ser 347 (Accession # Q8R007-1).
-20°C
Nectin-4
Fc Tag
Less than 0.1 EU / µg by the LAL method.
Powder
Mouse
60.8 kDa
100 µg
Gly 31 - Ser 347
NECTIN4,LNIR, PRR4, PVRL4
Unconjugated
50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
HEK293
Immune Checkpoint Proteins
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SDS
Documenti
Certificati
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