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PD-L1/CD274 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 17952-1-AP-20UL

Dettagli aggiuntivi : Peso : 0.00010kg

 vedi altre versioni di questo prodotto

Codice prodotto. 16897964

  • 129.00€ / 20µL

Spedizione stimata: 19-12-2022
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Descrizione

Descrizione

PD-L1 (Programmed death receptor ligand 1, B7-H1, CD274) is a 40 kDa transmembrane protein and B7 family member. PD-L1 has been shown to negatively regulate T-cell receptor (TCR) signaling. Upon ligating its receptor, PD-L1 has been reported to decrease TCR-mediated proliferation and cytokine production, and PD-L1 expression was found to be abundant on many murine and human cancers and could be further up-regulated upon IFN-gamma stimulation. Thus, PD-L1 might play an important role in tumor immune evasion. Together with B7.1, PD-L1 can inactivate T cells and this relationship is a focal point of cancer therapeutic treatment. At least two isoforms of PDL-1 are known to exist.
Specifica

Specifica

PD-L1/CD274
Polyclonal
Unconjugated
CD274
PD-L1/CD274
Rabbit
Antigen Affinity Chromatography
RUO
29126, 499342, 60533
-20°C
Liquid
Immunohistochemistry (Paraffin), Immunocytochemistry, Immunoprecipitation, Flow Cytometry, Immunofluorescence
0.33 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q9EP73, Q9NZQ7
CD274
PD-L1/CD274 Fusion Protein Ag12432
20 μL
Primary
Mouse, Rat, Human
Antibody
IgG
Videos
SDS
Documenti
Certificati
Offerte speciali

Offerte speciali