PPARA Mouse anti-Human, Clone: 1G1E10, Proteintech
Mouse Monoclonal Antibody
Marca: Proteintech 66826-1-IG-150UL
Dettagli aggiuntivi : Peso : 0.00010kg
DescrizionePeroxisome proliferators are non-genotoxic carcinogens which are purported to exert their effect on cells through their interaction with members of the nuclear hormone receptor family termed peroxisome proliferator activated receptors (PPAR′s). Nuclear hormone receptors are ligand-dependent intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate ligand. Studies indicate that PPAR′s are activated by peroxisome proliferators such as clofibric acid, nafenopin, and WY-14,643, as well as by some fatty acids. It has also been shown that PPAR′s can induce transcription of acyl coenzyme A oxidase & cytochrome P450 (CYP450) A6 through interaction with specific response elements. PPAR, like several other nuclear hormone receptors, heterodimerizes with retinoid X receptor (RXR) alpha.
|PBS with 50% glycerol and 0.1% sodium azide; pH 7.3|
|PPARA Fusion Protein Ag7896|
|hPPAR, NR1C1, PPAR, PPAR alpha, PPARA|