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Securin / PTTG1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 18040-1-AP-20UL

Dettagli aggiuntivi : Peso : 0.00010kg

 vedi altre versioni di questo prodotto

Codice prodotto. 16898074

  • 129.00€ / 20µL

Spedizione stimata: 19-12-2022
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Descrizione

Descrizione

Pituitary tumor-transforming gene 1 (PTTG-1) is an oncogene expressed in normal tissues containing proliferating cells and in tumors. PTTG is downstream of the MAP kinase signaling cascade and is phosphorylated at Ser162 by MAPK in vitro. Phosphorylation plays an essential role in PTTG′s transactivation function. The PTTG protein contains a DNA-binding domain, and it activates transcription of the c-Myc oncogene by binding to the promoter to form a complex. Studies have demonstrated that expression of human PTTG correlates with cell proliferation in a cell cycle dependent manner, and the association of human PTTG with Ku, the regulatory subunit of DNA-dependent protein kinase, is disrupted when a DNA double-strand breaks occurs.
Specifica

Specifica

Securin / PTTG1
Polyclonal
Unconjugated
PTTG1
EAP1, Esp1 associated protein, HPTTG, pituitary tumor transforming 1, PTTG, PTTG1, Securin, Tumor transforming protein 1, TUTR1
Rabbit
Antigen Affinity Chromatography
RUO
30939, 64193, 9232
-20°C
Liquid
Immunocytochemistry, Immunofluorescence
0.38 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O95997, P97613, Q9CQJ7
Pttg1
Securin / PTTG1 Fusion Protein Ag12670
20 μL
Primary
Human, Rat, Mouse
Antibody
IgG
Videos
SDS
Documenti
Certificati
Offerte speciali

Offerte speciali