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SPHK2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 17096-1-AP-20UL

Dettagli aggiuntivi : Peso : 0.00010kg

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Codice prodotto. 16896934

  • 121.38€ / 20µL

Spedizione stimata: 11-10-2022
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Descrizione

Descrizione

Sphingosine Kinase 2 (Sphk2) catalyzes the phosphorylation of sphingosine to sphingosine 1-phosphate (S1P), an important signaling molecule with intra- and extracellular functions. Inside the cell S1P acts as a signaling molecule like other sphingolipid metabolites like ceramide and sphingosine. S1P has been implicated in regulating cell differentiation, calcium mobilization from intracellular stores, and apoptosis. The cell surface receptors for S1P are the EDG family of G protein-coupled receptors (S1P Receptors). These receptors couple to multiple G proteins (e.g. S1P1 couples to Gi whereas S1P2 and S1P3 couple to Gq, G13 in addition to Gi) and regulate a extremely wide raange of cellular events including cell motility, survival, apoptosis, migration and cell-cell interaction. Important roles for S1P have also been reported in regulation of cardiogenesis, vascular maturation, oocyte survival, immune cell trafficking, cells of the neuronal system and bone cells. S1P levels are regulated by the activity of Sphk (Sphk1 and Sphk2).
Specifica

Specifica

SPHK2
Polyclonal
Unconjugated
SPHK2
SK 2, sphingosine kinase 2, SPHK2, SPK 2
Rabbit
Antigen Affinity Chromatography
RUO
308589, 56632, 56848
-20°C
Liquid
Immunofluorescence, Immunoprecipitation, Western Blot, Immunohistochemistry (Paraffin), Immunocytochemistry
0.27 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q9JIA7, Q9NRA0
Sphk2
SPHK2 Fusion Protein Ag10569
20 μL
Primary
Human, Rat, Mouse
Antibody
IgG
Videos
SDS
Documenti
Certificati
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Offerte speciali