Ruxolitinib, Thermo Scientific™

Ruxolitinib, Mikromol™

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(R)-Ruxolitinib (>90%), TRC

CAS: 941678-49-5 Formula molecolare: C17 H18 N6 Molecular Weight (g/mol): 306.365 Sinonimo: (βR)-β-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile,(3R)-3-Cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile,(βR)-β-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile,INC 424,INCB 018424,Ruxolitinib IUPAC Name: (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile SMILES: N#CC[C@H](C1CCCC1)n2cc(cn2)c3ncnc4[nH]ccc34

Tocris Bioscience™ Ruxolitinib

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Potent and selective JAK1/JAK2 inhibitor; orally bioavailable

Ruxolitinib, MedChemExpress

MedChemExpress Ruxolitinib (INCB18424) is a potent and selective JAK1/2 inhibitor with IC50s of 3.3 nM and 2.8 nM in cell-free assays, and has 130-fold selectivity for JAK1/2 over JAK3. Ruxolitinib induces autophagy and kills tumor cells through toxic mitophagy.

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