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Crosslinking Reagents

Reagents containing reactive end groups that respond to the presence of specific functional groups by forming bonds between polymer chains. Ideal for various applications including conjugation reactions, biomolecule labeling, and molecular purification.
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1 – 15 di 93 risultati
1

Thermo Scientific™ Crosslinker Pierce™ EDC

Immobilize or conjugate proteins using 1-Ethyl-3-(3-dimethylaminopropyl) carbodiimide (CAS 25952-53-8), a water-soluble, carboxyl-to-amine crosslinker.

EDGE
Shipping Condition Wet Ice
Content And Storage Upon receipt store desiccated at -20°C.
Cleavable No
Permeabilità celle No
Descrizione EDC
Solubile in acqua Yes
Labeling Method Chemical Labeling
Crosslinker Type Heterobifunctional
Chemical Reactivity Amine-Carboxyl
Formato Standard, Single-use, Premium-grade
Lunghezza braccio spaziatore 0.0 Å
Peso molecolare 191.7
Forma Powder
Product Type Crosslinker
Spacer Short (<10 Å)
Reactive Moiety Carbodiimide
Solubilità Water
PEGylated No
2

Thermo Scientific™ Crosslinker Pierce™ Sulfo-SMCC

Crosslink amines to sulfhydryls with this mid-length, water-soluble crosslinker made of NHS-ester and maleimide groups at ends of a cyclohexane-containing, 8-atom spacer arm.

EDGE
Shipping Condition Ambient
Content And Storage Upon receipt store desiccated at -20°C.
Cleavable No
Permeabilità celle No
Descrizione Sulfo-SMCC
Solubile in acqua Yes
Labeling Method Chemical Labeling
Crosslinker Type Heterobifunctional
Chemical Reactivity Amine-Sulfhydryl
Formato Standard, Single-use, Premium-grade
Lunghezza braccio spaziatore 8.3 Å
Peso molecolare 436.37
Product Type Crosslinker
Spacer Short (<10 Å)
Reactive Moiety Maleimide, Sulfo-NHS Ester
Solubilità Water
PEGylated No
3

Thermo Scientific™ Pierce™ Sulfo-SANPAH, No-Weigh™ Format

EDGE
Shipping Condition Ambient
Content And Storage Upon receipt store at -20°C protected from light and moisture.
Cleavable By Thiols
Permeabilità celle No
Solubile in acqua Yes
Labeling Method Chemical Labeling
Crosslinker Type Heterobifunctional
Chemical Reactivity Amine-Nonselective
Formato Standard, Single-use
Lunghezza braccio spaziatore 18.2 Å
Peso molecolare 492.4
Forma Powder
Product Type Crosslinker
Spacer Medium (10 to 30 Å)
Solubilità Water
PEGylated No
4

Thermo Scientific™ NHS-PEG4-Azide

Activated azido compounds to derivatize proteins or amine surfaces for selective conjugation, detection or purification by phosphine-modified probes.

EDGE
5
Promozioni disponibili

Thermo Scientific™ Pierce™ SMCC

No-Weigh™ Format

Shipping Condition Ambient
Content And Storage Upon receipt store desiccated at 4°C.
Cleavable By Thiols
Permeabilità celle Yes
Solubile in acqua No
Labeling Method Chemical Labeling
Crosslinker Type Heterobifunctional
Chemical Reactivity Amine-Sulfhydryl
Formato Standard, Single-use
Lunghezza braccio spaziatore 8.3 Å
Peso molecolare 334.32
Forma Powder
Product Type Crosslinker
Spacer Short (<10 Å)
Reactive Moiety Maleimide, NHS Ester
Solubilità DMF, DMSO
PEGylated No
6

Thermo Scientific™ Crosslinker Pierce™ DTSSP

Crosslink amines to amines with Sulfo-DSP; composed of sulfo-NHS-ester groups and disulfide spacer arm (12.0A) that is cleavable with reducing agents.

7

Thermo Scientific™ Mass Spectrometry Cleavable Crosslinkers

Improve sensitivity of mass spectrometry detection of crosslinked proteins with MS-cleavable DSSO and DSBU heterotrifunctional crosslinkers.

Content And Storage Upon receipt store at 4°C protected from moisture.
Cleavable By CID using MS
Permeabilità celle Yes
Solubile in acqua No
Labeling Method Chemical Labeling
Crosslinker Type Homobifunctional
Chemical Reactivity Amine-Amine
Formato Standard, Single-use
Quantità 10 x 1 mg
Forma Powder
Product Type Crosslinker
Spacer Medium (10 to 30 Å)
Reactive Moiety NHS Ester
Solubilità DMF, DMSO
PEGylated No
8

Thermo Scientific™ Crosslinker Pierce™ DSS

Crosslink amines to amines with disuccinimidyl suberate composed of NHS-ester groups with a membrane-permeable, mid-length spacer for intracellular protein crosslinking.

EDGE
Cleavable No
PEGylated No
9

Thermo Scientific™ Crosslinker Pierce™ DSP

Crosslink amines to amines with dithiobis succinimidyl propionate, composed of NHS-ester groups and disulfide-containing, 12.0A spacer arm and cleavable with reducing agents.

EDGE
Content And Storage Upon receipt store desiccated at 4°C.
Cleavable By Thiols
Permeabilità celle Yes
Descrizione DSP
Solubile in acqua No
Labeling Method Chemical Labeling
Crosslinker Type Homobifunctional
Chemical Reactivity Amine-Amine
Formato Standard, Single-use, Premium-grade
Lunghezza braccio spaziatore 12.0 Å
Peso molecolare 404.42
Forma Powder
Product Type Crosslinker
Spacer Medium (10 to 30 Å)
Reactive Moiety NHS Ester
Solubilità DMF, DMSO
PEGylated No
10

Thermo Scientific™ LC-SMCC (succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxy-(6-amidocaproate))

Crosslink amines to sulfhydryls with this long crosslinker composed of NHS-ester and maleimide groups at ends of a stabilizing cyclohexane-containing, 15-atom spacer arm.

EDGE
11

Thermo Scientific™ Pierce™ Premium Grade DSP (dithiobis(succinimidyl propionate))

Optimize applications where product integrity and risk minimization are paramount with our highest quality formulation of this popular amine-reactive, cleavable crosslinker.

EDGE
Shipping Condition Ambient
Content And Storage Upon receipt store desiccated at 4°C.
Cleavable By Thiols
Permeabilità celle Yes
Linea di prodotti Pierce
Solubile in acqua No
Labeling Method Chemical Labeling
Crosslinker Type Homobifunctional
Chemical Reactivity Amine-Amine
Formato Standard, Single-use, Premium-grade
Lunghezza braccio spaziatore 12.0 Å
Peso molecolare 404.42
Forma Powder
Product Type Crosslinker
Spacer Medium (10 to 30 Å)
Reactive Moiety NHS Ester
Solubilità DMF, DMSO
Formulazione Dithiobis(succinimidylpropionate); powder solid
PEGylated No
12

Thermo Scientific™ Crosslinker Pierce™ EGS

Crosslink amines to amines with this membrane permeable crosslinker composed of NHS-ester groups and a 16.1A hydroxylamine-cleavable spacer arm.

EDGE
13

Thermo Scientific™ Pierce™ DSG, No-Weigh™ Format

EDGE
Cleavable No
Permeabilità celle Yes
Solubile in acqua No
Labeling Method Chemical Labeling
Crosslinker Type Homobifunctional
Chemical Reactivity Amine-Amine
Formato Standard, Single-use
Lunghezza braccio spaziatore 7.7 Å
Peso molecolare 326.26
Forma Powder
Product Type Crosslinker
Spacer Short (<10 Å)
Reactive Moiety NHS Ester
Solubilità DMF, DMSO
PEGylated No
14
Promozioni disponibili

Thermo Scientific™ Crosslinker Pierce™ BS(PEG)n

Crosslink amines to amines with these long (21.7A and 35.8A) crosslinkers composed of NHS-ester groups and 5-unit or 9-unit PEG spacer arms that enhance protein solubility.

EDGE
15

Thermo Scientific™ Crosslinker Pierce™ DMP

Crosslink amines to amines with dimethyl pimelimidate (CAS 58537-94-3); composed of imidoester groups and a membrane-permeable, 7-atom spacer arm.

EDGE
Shipping Condition Ambient
Content And Storage Upon receipt store desiccated at 4°C.
Cleavable No
Permeabilità celle Yes
Descrizione DMP
Linea di prodotti Pierce
Solubile in acqua Yes
Labeling Method Chemical Labeling
Crosslinker Type Homobifunctional
Chemical Reactivity Amine-Amine
Formato Standard
Lunghezza braccio spaziatore 9.2 Å
Peso molecolare 259.17
Forma Powder
Product Type Crosslinker
Spacer Short (<10 Å)
Reactive Moiety Imidoester
Solubilità Water
PEGylated No